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Coadministration of branched-chain amino acids and lipopolysaccharide causes matrix metalloproteinase activation and blood-brain barrier breakdown.
Scaini G, Morais MO, Galant LS, Vuolo F, Dall'Igna DM, Pasquali MA, Ramos VM, Gelain DP, Moreira JC, Schuck PF, Ferreira GC, Soriano FG, Dal-Pizzol F, Streck EL. Scaini G, et al. Among authors: ramos vm. Mol Neurobiol. 2014 Oct;50(2):358-67. doi: 10.1007/s12035-013-8618-0. Epub 2014 Jan 5. Mol Neurobiol. 2014. PMID: 24390570
Hecogenin acetate inhibits reactive oxygen species production and induces cell cycle arrest and senescence in the A549 human lung cancer cell line.
Gasparotto J, Somensi N, Kunzler A, Girardi CS, de Bittencourt Pasquali MA, Ramos VM, Simoes-Pires A, Quintans-Junior LJ, Branco A, Moreira JC, Gelain DP. Gasparotto J, et al. Anticancer Agents Med Chem. 2014;14(8):1128-35. doi: 10.2174/1871520614666140408151751. Anticancer Agents Med Chem. 2014. PMID: 25115457